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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
PA1-4325 detects CRG-L2 in human samples.
PA1-4325 has been successfully used in Western blotting procedures. The predicted molecular weight is 48 kDa. By Western blot, this antibody detects a protein often above ~50 kDa representing CRG-L2. This protein can form dimers.
PA1-4325 immunizing peptide corresponds to amino acid residues 160-176 of human CRG-L2.
CRG-L2 is a protein that contains olfactomedin-like and collagen-like domains. The encoded protein, which exists in both transmembrane and secreted forms, promotes formation of the nodes of Ranvier in the peripheral nervous system. Mutations in this gene cause a form of lethal congenital contracture syndrome in human patients. Autoantibodies to the encoded protein have been identified in sera form patients with multifocal motor neuropathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。