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Invitrogen
mGluR6 Polyclonal Antibody
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图: 1 / 2
mGluR6 Antibody (PA1-46253) in ICC/IF
Immunocytochemistry analysis of mGluR6 in trapezoid body in mouse brain. Samples were incubated in mGluR6 polyclonal antibody (Product # PA1-46253) followed by anti-rabbit Cy3 conjugated secondary antibodies (red). DAPI was used to counterstain cell nuclei.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA1-46253
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C-terminus of rat metabotropic Glutamate Receptor 6 (mGluR6).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody reacts weakly on human brain tissue.
靶标信息
Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor GRM6; G protein-coupled receptor, family C, group 1, member F; glutamate receptor; Metabotropic glutamate receptor 6; mGluR6
基因别名: BC021919; Gm3; Gprc1f; Grm6; Mglur6; nerg1; nob2; nob3; nob4
UniProt ID: (Rat) P35349, (Mouse) Q5NCH9
Entrez Gene ID: (Rat) 24419, (Mouse) 108072
signal transduction
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
locomotory behavior
detection of light stimulus involved in visual perception
sensory perception of light stimulus
regulation of synaptic transmission, glutamatergic
retina development in camera-type eye
positive regulation of calcium ion import
G-protein coupled receptor signaling pathway
visual perception
response to stimulus
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