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Invitrogen
Syntrophin alpha-1 Polyclonal Antibody
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FIGURE: 1 / 3
Syntrophin alpha-1 Antibody (PA1-9107) in WB
Western blot analysis of Syntrophin alpha-1 using Syntrophin alpha-1 Polyclonal Antibody (Product # PA1-9107) (0.01 µg/mL) in staining of Human Muscle lysate (35 µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-9107
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the N terminus amino acids ASGRRAPRTGLLE (aa 2-14).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, canine and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Syntrophin alpha-1 (Dystrophin, SNTA1) is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 59 kDa dystrophin-associated protein A1 acidic component 1; Alpha-1-syntrophin; alpha1-syntrophin; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; RP23-192L3.1; syntrophin, acidic 1; Syntrophin-1; TACIP1
Gene Aliases: AW228934; SNT1; SNTA1
Entrez Gene ID: (Mouse) 20648, (Rat) 362242
regulation of heart rate
regulation of vasoconstriction by circulating norepinephrine
neuromuscular junction development
regulation of ventricular cardiac muscle cell membrane repolarization
ventricular cardiac muscle cell action potential
negative regulation of peptidyl-cysteine S-nitrosylation
regulation of sodium ion transmembrane transport
biological_process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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