Search
Invitrogen
ANGPTL3 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-95123
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human ANGPTL3 (32-48aa EPKSRFAMLDDVKILAN).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: A549 Cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ANG-5; angiopoietin 5; Angiopoietin-5; Angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGPTL3; hypolipidemia; unnamed protein product
Gene Aliases: ANG-5; ANGPT5; ANGPTL3; ANL3; FHBL2; hypl; UNQ153/PRO179
UniProt ID: (Human) Q9Y5C1, (Mouse) Q9R182
Entrez Gene ID: (Human) 27329, (Mouse) 30924, (Rat) 502970
angiogenesis
glycerol metabolic process
lipid metabolic process
fatty acid metabolic process
phospholipid metabolic process
cell adhesion
cell-matrix adhesion
signal transduction
integrin-mediated signaling pathway
cholesterol metabolic process
phospholipid catabolic process
response to hormone
negative regulation of very-low-density lipoprotein particle remodeling
lipid storage
positive regulation of cell migration
cholesterol homeostasis
positive regulation of angiogenesis
artery morphogenesis
positive regulation of lipid catabolic process
lipid homeostasis
acylglycerol homeostasis
phospholipid homeostasis
triglyceride homeostasis
regulation of chylomicron remodeling
triglyceride metabolic process
negative regulation of phospholipase activity
negative regulation of catalytic activity
positive regulation of lipid metabolic process
negative regulation of lipoprotein lipase activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support