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Calcitonin Polyclonal Antibody

查看其他26个Calcitonin抗体

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Calcitonin Polyclonal Antibody

产品信息

PA5-95529

应用
建议稀释比
已发表文章

免疫组化（石蜡） (IHC (P))

0.5-1 µg/mL
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence of mouse Calcitonin (CGNLSTCMLGTYTQDLNKFHTFPQTSIGVEAP) (aa 85-116).
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

500 µg/mL

规格

100 µg

纯化类型

Affinity chromatography

保存液

PBS with 4mg trehalose

内含物

0.05mg sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2807331

产品详细信息

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Positive Control - IHC: mouse brain tissue, rat brain tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

靶标信息

Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Alpha CGRP; Alpha type CGRP; Alpha-type CGRP; Calcitonin; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related protein; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin precursor; calcitonin/calcitonin-related polypeptide, alpha; CGRP-I; CGRP1; katacalcin; katacalcin (KC); unnamed protein product

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基因别名: CA; Cal1; CAL6; Calc; CALC1; CALCA; calcitonin; CGRP; CGRP-1; CGRP-alpha; CGRP-I; CGRP1; CT; Ctn; KC; PCT; RATCAL6

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UniProt ID: (Rat) P01256, (Mouse) Q99JA0

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Entrez Gene ID: (Human) 796, (Rat) 24241, (Mouse) 12310

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功能
receptor binding hormone activity protein binding calcitonin receptor binding identical protein binding macromolecular complex binding receptor agonist activity neuropeptide hormone activity protein complex binding peptide hormone
参与通路
response to yeast endothelial cell proliferation vasculature development neurological system process involved in regulation of systemic arterial blood pressure G-protein coupled receptor internalization monocyte chemotaxis protein phosphorylation leukocyte cell-cell adhesion adenylate cyclase-activating G-protein coupled receptor signaling pathway activation of adenylate cyclase activity phospholipase C-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration cell-cell signaling embryo implantation regulation of blood pressure negative regulation of calcium ion transport into cytosol antibacterial humoral response antifungal humoral response receptor internalization activation of protein kinase activity positive regulation of interleukin-1 alpha production positive regulation of interleukin-8 production vasodilation endothelial cell migration innate immune response positive regulation of macrophage differentiation negative regulation of osteoclast differentiation negative regulation of blood pressure negative regulation of bone resorption negative regulation of transcription, DNA-templated negative regulation of smooth muscle contraction defense response to Gram-negative bacterium defense response to Gram-positive bacterium regulation of cytosolic calcium ion concentration antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to tumor necrosis factor calcitonin family receptor signaling pathway amylin receptor 1 signaling pathway amylin receptor 2 signaling pathway cellular response to nerve growth factor stimulus calcitonin gene-related peptide receptor signaling pathway vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure regulation of heart rate cellular calcium ion homeostasis inflammatory response neuropeptide signaling pathway neuromuscular junction development aging feeding behavior regulation of heart contraction response to heat negative regulation of ossification positive regulation of cAMP biosynthetic process negative regulation of neurological system process positive regulation of adenylate cyclase activity positive regulation of ossification positive regulation of cell adhesion positive regulation of vasodilation response to pain detection of temperature stimulus involved in sensory perception of pain positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway sperm capacitation mitophagy in response to mitochondrial depolarization
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