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Invitrogen
ACSL4 Polyclonal Antibody
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图: 1 / 18
ACSL4 Antibody (PA5-100033) in ICC/IF
Immunofluorescent analysis of ACSL4 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and ACSL4 polyclonal antibody (Product # PA5-100033) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100033
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ACSL4(Accession O60488), corresponding to amino acid residues Y31-K81.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ACSL4/FACL4.
靶标信息
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Arachidonate--CoA ligase; fatty acid Coenzyme A ligase, long chain 4; fatty acid-Coenzyme A ligase long chain 4; fatty acid-Coenzyme A ligase, long chain 4; L MRX63; LACS 4; Long-chain acyl-CoA synthetase 4; Long-chain-fatty-acid--CoA ligase 4; mACS4
基因别名: 9430020A05Rik; ACS4; ACSL4; AU018108; FACL4; LACS4
UniProt ID: (Rat) O35547, (Mouse) Q9QUJ7
Entrez Gene ID: (Rat) 113976, (Mouse) 50790
long-chain fatty acid metabolic process
lipid metabolic process
fatty acid metabolic process
triglyceride metabolic process
response to nutrient
lipid biosynthetic process
fatty acid transport
neuron differentiation
positive regulation of cell growth
negative regulation of prostaglandin secretion
embryonic process involved in female pregnancy
dendritic spine development
response to interleukin-15
metabolic process
regulation of fatty acid metabolic process
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