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Invitrogen
Katanin p80 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100274
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human KATNB1(Accession Q9BVA0), corresponding to amino acid residues L333-N383.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total KATNB1.
Target Information
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: katanin (80 kDa); katanin p80 (WD repeat containing) subunit B 1; katanin p80 (WD40-containing) subunit B 1; Katanin p80 subunit B1; Katanin p80 WD40 repeat-containing subunit B1; katanin p80 WD40-containing subunit B1; KATNB1; p80 katanin
Gene Aliases: 2410003J24Rik; KAT; KATNB1; LIS6
UniProt ID: (Mouse) Q8BG40
Entrez Gene ID: (Human) 10300, (Mouse) 74187, (Rat) 291852
negative regulation of microtubule depolymerization
cell cycle
mitotic nuclear division
metabolic process
positive regulation of cell death
positive regulation of neuron projection development
positive regulation of microtubule depolymerization
microtubule severing
cell division
mitotic chromosome movement towards spindle pole
protein targeting
microtubule depolymerization
cytoplasmic microtubule organization
positive regulation of apoptotic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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