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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total PIH1D1.
Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription (PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex (PubMed:24036451).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Nucleolar protein 17 homolog; PIH1 domain-containing protein 1
基因别名: 1110061L23Rik; 4933413A04Rik; NOP17; PIH1D1; RGD1309809
UniProt ID: (Mouse) Q9CQJ2, (Rat) Q4V7F5
Entrez Gene ID: (Mouse) 68845, (Rat) 292898