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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total PLEKHG5.
Guanine nucleotide exchange factor that activates RHOA and maybe the NF-kappa-B signaling pathway. Involved in the control of neuronal cell differentiation. Plays a role in angiogenesis through regulation of endothelial cells chemotaxis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: guanine nucleotide exchange factor 720; neuronal RhoA GEF protein; NFkB activating protein; novel PH domain-containing protein; PH domain-containing family G member 5; pleckstrin homology domain containing, family G (with RhoGef domain) member 5; RhoA-specific guanine exchange factor SYX1; RhoA-specific guanine exchange factor SYX2; synectin-binding guanine exchange factor; synectin-binding RhoA exchange factor; TECH; transcript highly enriched in cortex and hippocampus; unnamed protein product
Gene Aliases: ARHGEF45; CMTRIC; DSMA4; GEF720; HMNR4; Syx; Tech
UniProt ID: (Human) O94827, (Mouse) Q66T02, (Rat) Q6RFZ7
Entrez Gene ID: (Human) 57449, (Mouse) 269608, (Rat) 310999
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