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Invitrogen
SIVA1 Polyclonal Antibody
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SIVA1 Antibody (PA5-100737) in ICC/IF
Immunocytochemistry analysis of SIVA1 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SIVA1 polyclonal antibody (Product # PA5-100737) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100737
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SIVA1(Accession O15304), corresponding to amino acid residues V65-S115.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SIVA.
靶标信息
Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alternate splice form of Siva-1; Cd27 binding protein; CD27-binding (Siva) protein; CD27-binding protein; similar to Homo sapiens Siva encoded by GenBank Accession Number U82938; Siva; unnamed protein product
基因别名: CD27BP; SIVA; Siva-1; Siva-2
UniProt ID: (Human) O15304, (Mouse) O54926
Entrez Gene ID: (Human) 10572, (Mouse) 30954
activation-induced cell death of T cells
negative regulation of I-kappaB kinase/NF-kappaB signaling
viral entry into host cell
T cell receptor signaling pathway
T cell apoptotic process
extrinsic apoptotic signaling pathway
intrinsic apoptotic signaling pathway
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
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