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Invitrogen
Laminin beta-3 Polyclonal Antibody
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FIGURE: 1 / 5
Laminin beta-3 Antibody (PA5-100746) in ICC/IF
Immunocytochemistry analysis of Laminin beta-3 in HepG2 cells (serum starvation treatment). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Laminin beta-3 polyclonal antibody (Product # PA5-100746) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L)... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100746
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human LAMB3(Accession Q13751), corresponding to amino acid residues Q518-Q568.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total LAMB3.
Target Information
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epiligrin subunit bata; Epiligrin subunit beta; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin subunit beta-3; Laminin-5 subunit beta; Nicein subunit beta; nicein, 125kD; nicein, 125kDa; nicein-125k; RP1-272L16.3
Gene Aliases: LAMB3; LAMNB1
UniProt ID: (Mouse) Q61087
Entrez Gene ID: (Mouse) 16780
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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