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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total NKIRAS2.
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: I-kappa-B-interacting Ras-like protein 2; Kappa B-Ras protein 2; kappaB-Ras2; NF-kappa-B inhibitor-interacting Ras-like protein 2
基因别名: 2410003M04Rik; 4930527H08Rik; D630018G21Rik; KBRAS2; NKIRAS2
UniProt ID: (Mouse) Q9CR56
Entrez Gene ID: (Mouse) 71966