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Invitrogen
THRAP4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-101073
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MED24(Accession O75448), corresponding to amino acid residues V814-N864.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total MED24.
Target Information
This gene encodes a component of the mediator complex, a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activator-recruited cofactor 100 kDa component; ARC100; Cofactor required for Sp1 transcriptional activation subunit 4; CRSP complex subunit 4; DRIP100; genetic suppressor element 2; hTRAP100; Mediator complex subunit 24; Mediator of RNA polymerase II transcription subunit 24; MGC8748; mTRAP100; peroxisome proliferation activation receptor binding protein 2; thyroid hormone receptor associated protein 4; thyroid hormone receptor-associated protein 100 kDa; Thyroid hormone receptor-associated protein 4; Thyroid hormone receptor-associated protein complex 100 kDa component; Trap100; Vitamin D3 receptor-interacting protein complex 100 kDa component
Gene Aliases: 911GSE; ARC100; AU040102; AW547152; CRSP4; D11Ertd307e; DRIP100; Gse2; KIAA0130; MED24; Pparb2; Pparbp2; R75526; THRAP4; TRAP100
UniProt ID: (Rat) Q4V8B3, (Mouse) Q99K74
Entrez Gene ID: (Rat) 619436, (Mouse) 23989
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
protein ubiquitination
histone acetylation
stem cell population maintenance
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
protein heterooligomerization
transcription, DNA-templated
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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