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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total NFYB.
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of three subunits, NF-YA, NF-YB and NF-YC. All three components are necessary for DNA binding. In each NF-Y subunit, the segment needed for formation of the NF-Y-DNA complex is conserved from yeast to human. These conserved segments are homologous to the histone-fold motif of eukaryotic histones. The DNA-binding domains of the NF-YB and NF-YC subunits have been suggested to interact through a protein-protein, histone-fold "handshake" motif in a manner analogous to the histone proteins H2B and H2A, respectively.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CAAT box DNA-binding protein subunit B; CAAT-box DNA-binding protein subunit B; CBF-A; CBF-B; CCAAT binding transcription factor of CBF-B/NFY-B; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; nf-y; NF-YB; nuclear transcription factor - Y beta; Nuclear transcription factor Y subunit B; Nuclear transcription factor Y subunit beta
基因别名: AA985999; Cbf-A; CBF-B; CBFB; HAP3; Nfya; NFYB
UniProt ID: (Mouse) P63139, (Rat) P63140
Entrez Gene ID: (Mouse) 18045, (Rat) 25336