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Invitrogen
XRN2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-101255
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human XRN2(Accession Q9H0D6), corresponding to amino acid residues V92-K142.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total XRN2.
靶标信息
XRN2 gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5'-3' exoribonuclease 2; DHM1-like protein; DHP protein; Protein Dhm1; XRN2b
基因别名: Dhm1; XRN2
UniProt ID: (Mouse) Q9DBR1
Entrez Gene ID: (Mouse) 24128
3'-5'-exoribonuclease activity
transcription termination site sequence-specific DNA binding
nucleic acid binding
DNA binding
nuclease activity
exonuclease activity
5'-3' exoribonuclease activity
protein binding
zinc ion binding
5'-3' exonuclease activity
hydrolase activity
poly(A) RNA binding
metal ion binding
exoribonuclease
DNA catabolic process, exonucleolytic
nucleobase-containing compound metabolic process
DNA repair
DNA recombination
transcription, DNA-templated
DNA-templated transcription, termination
regulation of transcription, DNA-templated
mRNA processing
microtubule-based process
cell growth
RNA metabolic process
RNA phosphodiester bond hydrolysis, exonucleolytic
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