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Invitrogen
EXO1 Polyclonal Antibody
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EXO1 Antibody (PA5-101332) in IHC (P)
Immunohistochemistry analysis of EXO1 in rat testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with EXO1 polyclonal antibody (Product # PA5-101332) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-101332
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human EXO1(Accession Q9UQ84), corresponding to amino acid residues L66-R116.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total EXO1.
靶标信息
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Required for muscle atrophy following denervation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Exonuclease 1; Exonuclease I; hExo1; hExoI; mExo1
基因别名: 5730442G03Rik; EXO1; EXOI; HEX1; Msa
UniProt ID: (Mouse) Q9QZ11
Entrez Gene ID: (Rat) 305000, (Mouse) 26909
molecular_function
DNA binding
5'-3' exodeoxyribonuclease activity
structure-specific DNA binding
single-stranded DNA 5'-3' exodeoxyribonuclease activity
flap endonuclease activity
double-stranded DNA 5'-3' exodeoxyribonuclease activity
catalytic activity
nuclease activity
endonuclease activity
exonuclease activity
5'-3' exonuclease activity
hydrolase activity
hydrolase activity, acting on ester bonds
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
metal ion binding
exodeoxyribonuclease
DNA catabolic process, endonucleolytic
DNA catabolic process, exonucleolytic
humoral immune response mediated by circulating immunoglobulin
mismatch repair
DNA recombination
biological_process
somatic hypermutation of immunoglobulin genes
isotype switching
immune system process
nucleobase-containing compound metabolic process
DNA repair
cellular response to DNA damage stimulus
meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
