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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total ZFYVE19.
Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Abscission/NoCut checkpoint regulator; ANCHR; Zinc finger FYVE domain-containing protein 19
基因别名: 1500041L05Rik; ANCHR; Zfyve19
UniProt ID: (Mouse) Q9DAZ9
Entrez Gene ID: (Mouse) 72008