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Invitrogen
IL11RA Polyclonal Antibody
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IL11RA Antibody (PA5-102002) in IHC (P)
Immunohistochemistry analysis of IL11RA in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with IL11RA polyclonal antibody (Product # PA5-102002) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102002
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human IL11RA(Accession Q14626), corresponding to amino acid residues W327-F377.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total IL11RA.
靶标信息
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Enhancer trap locus homolog 2; Etl-2; IL-11 receptor subunit alpha; IL-11 receptor subunit alpha-1; IL-11R subunit alpha; IL-11R subunit alpha-1; IL-11R-alpha; IL-11R-alpha-1; IL-11RA; Il-11ra-alpha; IL-11RA1; interleukin 11 receptor, alpha; interleukin 11 receptor, alpha chain 2; interleukin-11 receptor alpha chain; Interleukin-11 receptor subunit alpha; Interleukin-11 receptor subunit alpha-1; locus 2; Novel cytokine receptor 1; NR-1; sIL11RA; unnamed protein product
基因别名: AI314697; CRSDA; Etl2; GP130; Il-11ra; IL11RA; Il11ra1; Il11ra2; NR1
UniProt ID: (Rat) Q99MF4, (Mouse) Q64385
Entrez Gene ID: (Human) 3590, (Rat) 245983, (Mouse) 16157
negative regulation of cytokine-mediated signaling pathway
embryo implantation
positive regulation of cell proliferation
cytokine-mediated signaling pathway
B cell differentiation
megakaryocyte differentiation
developmental process
interleukin-11-mediated signaling pathway
positive regulation of MAPK cascade
negative regulation of cytokine activity
head development
natural killer cell differentiation
placenta development
decidualization
maternal process involved in female pregnancy
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