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Invitrogen
FZD3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102077
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FZD3(Accession Q9NPG1), corresponding to amino acid residues A146-R196.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total FZD3.
Target Information
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Frizzled-3; Fz-3; hFz3; mFz3
Gene Aliases: AU020229; D930050A07Rik; Fz3; FZD3
UniProt ID: (Mouse) Q61086
Entrez Gene ID: (Mouse) 14365
establishment of planar polarity
neuron migration
neural tube closure
positive regulation of neuroblast proliferation
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
multicellular organism development
nervous system development
Wnt signaling pathway
midbrain development
cell proliferation in midbrain
non-canonical Wnt signaling pathway
post-anal tail morphogenesis
inner ear morphogenesis
negative regulation of mitotic cell cycle, embryonic
canonical Wnt signaling pathway
sympathetic ganglion development
commissural neuron axon guidance
negative regulation of execution phase of apoptosis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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