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Invitrogen
RAB6A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102813
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RAB6A(Accession P20340), corresponding to amino acid residues R112-N162.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RAB6A.
Target Information
Rab proteins are also an integral part of endocytic pathways. Rab 6A is a ubiquitously expressed member of the Rab family of proteins and localizes to the Golgi membrane where it regulates retrograde transport from the late endosomes via the Golgi to endoplasmic reticulum (ER) pathway. Three isoforms exist due to alternative splicing events, namely the ubiquitously expressed isoforms Rab 6A' and Rab 6A, and the brain-specific isoform Rab 6B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Rab-6; RAB6, member RAS oncogene family; RAB6B, member RAS oncogene family; Ras-related protein Rab-6A
Gene Aliases: 2610028L11Rik; AA419671; MNCb-1660; RAB6; RAB6A; Rab6b; RCO4-3
UniProt ID: (Rat) Q9WVB1, (Mouse) P35279
Entrez Gene ID: (Rat) 84379, (Mouse) 19346
protein targeting to Golgi
intracellular protein transport
retrograde vesicle-mediated transport, Golgi to ER
intra-Golgi vesicle-mediated transport
metabolic process
peptidyl-cysteine methylation
antigen processing and presentation
Rab protein signal transduction
positive regulation of ATPase activity
protein localization to Golgi apparatus
early endosome to Golgi transport
retrograde transport, endosome to Golgi
Golgi vesicle transport
transport
small GTPase mediated signal transduction
protein transport
vesicle-mediated transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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