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Invitrogen
TC10 Polyclonal Antibody
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FIGURE: 1 / 2
TC10 Antibody (PA5-102866) in IHC (P)
Immunohistochemistry analysis of TC10 in rat heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with TC10 polyclonal antibody (Product # PA5-102866) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102866
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RHOQ(Accession P17081), corresponding to amino acid residues A111-V161.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RHOQ.
Target Information
TC10 is a member of the RAS superfamily of small GTP-binding proteins (see HRAS, MIM 190020) involved in insulin-stimulated glucose uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ras homolog gene family, member Q; Ras-like protein family member 7A; Ras-like protein TC10; ras-related GTP-binding protein TC10; Rho-related GTP-binding protein RhoQ; small GTPase Tc10
Gene Aliases: ARHQ; RASL7A; RHOQ; TC10; TC10A
UniProt ID: (Mouse) Q8R527, (Rat) Q9JJL4
Entrez Gene ID: (Mouse) 104215, (Rat) 85428
small GTPase mediated signal transduction
insulin receptor signaling pathway
regulation of cell shape
actin cytoskeleton organization
cortical actin cytoskeleton organization
cellular response to insulin stimulus
positive regulation of transcription from RNA polymerase II promoter
GTP metabolic process
negative regulation of glucose import
positive regulation of glucose import
positive regulation of filopodium assembly
negative regulation of establishment of protein localization to plasma membrane
metabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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