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Invitrogen
FUT4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-103133
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FUT4(Accession P22083), corresponding to amino acid residues S52-H102.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total FucT-IV.
Target Information
FUT4 (Fucosyltransferase 4) is a Protein Coding gene. Diseases associated with FUT4 include Colon Adenocarcinoma and Liver Lymphoma. Among its related pathways are Glycosphingolipid biosynthesis - lacto and neolacto series and Mannose type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include fucosyltransferase activity and alpha-(1->3)-fucosyltransferase activity. The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-fucosyl-N-acetyl-lactosamine epitope; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; alpha (1,3) fucosyltransferase, myeloid specific; alpha (1,3) fucosyltransferase, myeloid-specific; alpha 1,3-fucosyltransferase; alpha 1,3-fucosyltransferase Fuc-T (similar to mouse Fut4); alpha 13-fucosyltransferase Fuc-T (similar to mouse Fut4); ELAM ligand fucosyltransferase; ELAM-1 ligand fucosyltransferase; fuc-TIV; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); fucosyltransferase IV; fucT-IV; galactoside 3-L-fucosyltransferase; Lewis X; stage-specific embryonic antigen 1; unnamed protein product
Gene Aliases: CD15; ELFT; FAL; FCT3A; FUC-TIV; Fuct; FucT-IV; FUTIV; LeX; SSEA-1; Ssea1
UniProt ID: (Human) P22083, (Mouse) Q11127
Entrez Gene ID: (Human) 2526, (Rat) 60670, (Mouse) 14345
carbohydrate metabolic process
protein N-linked glycosylation
protein O-linked glycosylation
sphingolipid metabolic process
glycosphingolipid biosynthetic process
glycoprotein biosynthetic process
oligosaccharide metabolic process
oligosaccharide biosynthetic process
L-fucose catabolic process
lymphocyte migration into lymph node
Lewis x epitope biosynthetic process
positive regulation of neutrophil migration
regulation of leukocyte cell-cell adhesion
positive regulation of leukocyte tethering or rolling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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