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Invitrogen
Phospho-RRN3 (Ser649) Polyclonal Antibody
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Phospho-RRN3 (Ser649) Antibody (PA5-103273) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-RRN3 (Ser649) in mouse lung tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-RRN3 (Ser649) polyclonal antibody (Product # PA5-103273) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-103273
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RRN3(Accession Q9NYV6), corresponding to amino acid residues around phosphorylated Ser649.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of TIF1 alpha only when phosphorylated at Ser649.
靶标信息
Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RNA polymerase I-specific transcription initiation factor RRN3; TIF-IA; Transcription initiation factor IA; transcription initiation factor TIF-IA
基因别名: AL023001; E130302O19Rik; R75565; RGD1305001; RRN3; TIF-1A; Tif1a; TIFIA
UniProt ID: (Mouse) B2RS91
Entrez Gene ID: (Rat) 304714, (Mouse) 106298
in utero embryonic development
DNA-templated transcription, initiation
transcription initiation from RNA polymerase I promoter
nucleolus organization
cytoplasm organization
cell proliferation
positive regulation of neuron projection development
ribosome biogenesis
positive regulation of transcription, DNA-templated
homeostasis of number of cells
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
regulation of DNA-templated transcription, initiation
transcription, DNA-templated
regulation of transcription, DNA-templated
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