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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total SDCCAG8.
SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein that is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa and renal cancer tumors. Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder that is characterized by dysplasia or degeneration of the kidney, retina and cerebellum. SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on humanc chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Antigen NY-CO-8; Bardet-Biedl syndrome 16; Centrosomal colon cancer autoantigen protein; hCCCAP; mCCCAP; nephrocystin 10; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; unnamed protein product
基因别名: 2700048G21Rik; 5730470G24Rik; BBS16; CCCAP; CCCAP SLSN7; hCCCAP; HSPC085; NPHP10; NY-CO-8; SDCCAG8; SLSN7
UniProt ID: (Mouse) Q80UF4
Entrez Gene ID: (Human) 10806, (Mouse) 76816