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Invitrogen
Adenylate Cyclase 7 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-103390
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ADCY7(Accession P51828), corresponding to amino acid residues A751-F801.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ADCY7.
Target Information
This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AC7; similar to Homo sapiens AC7 and Bos taurus retinal pigment epithelium AC7; adenylate cyclase type VII; adenylyl cyclase 7; adenylyl cyclase type VII; ATP pyrophosphate-lyase 7; cyclic di-AMP synthase ADCY7; FLJ36387; KIAA0037; unnamed protein product
Gene Aliases: AC7
UniProt ID: (Human) P51828, (Mouse) P51829
Entrez Gene ID: (Human) 113, (Rat) 84420, (Mouse) 11513
regulation of adaptive immune response
cAMP biosynthetic process
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cyclic nucleotide biosynthetic process
positive regulation of toll-like receptor 9 signaling pathway
intracellular signal transduction
maternal process involved in female pregnancy
cellular response to lithium ion
cellular response to ethanol
negative regulation of cytokine production involved in inflammatory response
positive regulation of NLRP3 inflammasome complex assembly
renal water homeostasis
cellular response to glucagon stimulus
vascular endothelial cell response to laminar fluid shear stress
activation of adenylate cyclase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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