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Invitrogen
FGF20 Polyclonal Antibody
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FIGURE: 1 / 4
FGF20 Antibody (PA5-103410) in ICC/IF
Immunocytochemistry analysis of FGF20 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with FGF20 polyclonal antibody (Product # PA5-103410) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-103410
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FGF20(Accession Q9NP95), corresponding to amino acid residues Y151-P201.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total FGF20.
Target Information
FGF-20 is a secreted, heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-20 signals through FGFR 2c and 3c, and is expressed during limb and brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; Fibroblast growth factor; fibroblast growth factor 4a; unnamed protein product
Gene Aliases: FGF-20; Fgf4a; RHDA2
UniProt ID: (Human) Q9NP95, (Mouse) Q9ESL9, (Rat) Q9EST9
Entrez Gene ID: (Human) 26281, (Mouse) 80857, (Rat) 66017
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
neurogenesis
cell differentiation
regulation of cell migration
positive regulation of MAPK cascade
negative regulation of neuron apoptotic process
regulation of neuron differentiation
regulation of cardiac muscle cell proliferation
inner ear receptor cell differentiation
positive regulation of ERK1 and ERK2 cascade
signal transduction
cell-cell signaling
regulation of dopamine secretion
positive regulation of dopaminergic neuron differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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