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Invitrogen
MOZ Polyclonal Antibody
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MOZ Antibody (PA5-103467) in IHC (P)
Immunohistochemistry analysis of MOZ in human colorectal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with MOZ polyclonal antibody (Product # PA5-103467) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-103467
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KAT6A(Accession Q92794), corresponding to amino acid residues K198-L248.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total MYST3.
靶标信息
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Histone acetyltransferase KAT6A; histone acetyltransferase MYST3; Monocytic leukemia zinc finger homolog; Monocytic leukemia zinc finger protein; MOZ; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST histone acetyltransferase (monocytic leukemia) 3; MYST-3; Runt-related transcription factor-binding protein 2; Zinc finger protein 220
基因别名: 1500036M03; 9930021N24Rik; KAT6A; MOZ; MYST3; RUNXBP2; Zfp220; ZNF220
UniProt ID: (Rat) Q5TKR9
Entrez Gene ID: (Mouse) 244349, (Rat) 306571
DNA binding
chromatin binding
histone acetyltransferase activity
protein binding
transcription factor binding
zinc ion binding
acetyltransferase activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
metal ion binding
histone modifying enzyme
heart morphogenesis
nucleosome assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
protein acetylation
positive regulation of gene expression
chromatin modification
histone acetylation
myeloid cell differentiation
somatic stem cell population maintenance
embryonic hemopoiesis
aorta morphogenesis
negative regulation of sequence-specific DNA binding transcription factor activity
histone H3 acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
face morphogenesis
cellular senescence
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