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ABCA12 Polyclonal Antibody
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FIGURE: 1 / 2
ABCA12 Antibody (PA5-103631) in ICC/IF
Immunocytochemistry analysis of ABCA12 in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with ABCA12 polyclonal antibody (Product # PA5-103631) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-103631
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ABCA12(Accession Q86UK0), corresponding to amino acid residues Q2555-S2595.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ABCA12.
Target Information
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABCA12; ATP-binding cassette transporter 12; ATP-binding cassette, sub-family A (ABC1), member 12; DKFZp434G232; FLJ41584; unnamed protein product
Gene Aliases: ARCI4A; ARCI4B; ICR2B; LI2
UniProt ID: (Human) Q86UK0
Entrez Gene ID: (Human) 26154
receptor binding
lipid transporter activity
protein binding
ATP binding
ATPase activity
lipid-transporting ATPase activity
apolipoprotein A-I receptor binding
ATPase activity, coupled to transmembrane movement of substances
ATPase-coupled intramembrane lipid transporter activity
ABC-type transporter activity
corneocyte desquamation
ceramide metabolic process
lipid transport
intracellular protein transport
positive regulation of cholesterol efflux
cellular homeostasis
positive regulation of cholesterol transport
positive regulation of intracellular lipid transport
secretion by cell
phospholipid efflux
lipid translocation
ceramide transport
skin morphogenesis
regulated exocytosis
regulation of keratinocyte differentiation
transmembrane transport
regulation of insulin secretion involved in cellular response to glucose stimulus
establishment of skin barrier
protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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