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Invitrogen
KCNE3 Polyclonal Antibody
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图: 1 / 3
KCNE3 Antibody (PA5-104025) in IHC (P)
Immunohistochemistry analysis of KCNE3 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with KCNE3 polyclonal antibody (Product # PA5-104025) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-104025
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KCNE3(Accession Q9Y6H6), corresponding to amino acid residues M59-I103.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total KCNE3.
靶标信息
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Minimum potassium ion channel-related peptide 2; MinK-related peptide 2; MiRP2; Potassium channel subunit beta MiRP2; Potassium voltage-gated channel subfamily E member 3; potassium voltage-gated channel, Isk-related family, member 3; potassium voltage-gated channel, Isk-related subfamily, gene 3; potassium voltage-gated channel, Isk-related subfamily, member 3
基因别名: 2210017H05Rik; KCNE3; MiRP2
UniProt ID: (Rat) Q9JJV7, (Mouse) Q9WTW2
Entrez Gene ID: (Rat) 63883, (Mouse) 57442
regulation of potassium ion transport
regulation of membrane repolarization
potassium ion transmembrane transport
regulation of potassium ion transmembrane transport
positive regulation of voltage-gated calcium channel activity
negative regulation of voltage-gated potassium channel activity
transport
ion transport
potassium ion transport
regulation of ion transmembrane transport
negative regulation of delayed rectifier potassium channel activity
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