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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total RGS17.
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Regulator of G-protein signaling 17; regulator of G-protein signaling Z2; Regulator of Gz-selective protein signaling 2; RGS17
基因别名: 6430507P11Rik; RGS17; RGSZ2
UniProt ID: (Mouse) Q9QZB0
Entrez Gene ID: (Mouse) 56533