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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total TUSC3.
Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
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Protein Aliases: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3; Magnesium uptake/transporter TUSC3; MGC13453; Oligosaccharyl transferase subunit TUSC3; Protein N33; putative prostate cancer tumor suppressor; Tumor suppressor candidate 3
Gene Aliases: AU022242; BC003311; N33; TUSC3
UniProt ID: (Mouse) Q8BTV1
Entrez Gene ID: (Rat) 290783, (Mouse) 80286
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