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Invitrogen
Phospho-MEF2A (Ser408) Polyclonal Antibody
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FIGURE: 1 / 4
Phospho-MEF2A (Ser408) Antibody (PA5-104612) in IHC (P)
Immunohistochemistry analysis of Phospho-MEF2A (Ser408) in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-MEF2A (Ser408) polyclonal antibody (Product # PA5-104612) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-104612
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MEF2A(Accession Q02078), corresponding to amino acid residues around phosphorylated Ser408.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of MEF2A only when phosphorylated at Ser408.
Target Information
The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1
Gene Aliases: A430079H05Rik; MEF2; MEF2A
UniProt ID: (Mouse) Q60929, (Rat) Q2MJT0
Entrez Gene ID: (Mouse) 17258, (Rat) 309957
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II transcription coactivator activity
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein kinase binding
activating transcription factor binding
histone acetyltransferase binding
histone deacetylase binding
sequence-specific DNA binding
SMAD binding
protein heterodimerization activity
protein dimerization activity
mitochondrial genome maintenance
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
apoptotic process
multicellular organism development
nervous system development
cell differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
mitochondrion distribution
dendrite morphogenesis
ventricular cardiac myofibril assembly
cardiac conduction
ERK5 cascade
cellular response to calcium ion
heart development
cellular response to glucose stimulus
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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