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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of DOK2 only when phosphorylated at Tyrosine 299.
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Docking protein 2; Dok-R; Dok-related protein; Downstream of tyrosine kinase 2; FRIP; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; p56 dok-2; p56(dok-2)
基因别名: DOK2; DokR; Frip
UniProt ID: (Mouse) O70469
Entrez Gene ID: (Mouse) 13449