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Invitrogen
Phospho-BLNK (Tyr96) Polyclonal Antibody
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Phospho-BLNK (Tyr96) Antibody (PA5-105018) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-BLNK (Tyr96) in human lymph node tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-BLNK (Tyr96) polyclonal antibody (Product # PA5-105018) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105018
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human BLNK(Accession Q8WV28), corresponding to amino acid residues around phosphorylated Tyr96.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of BLNK only when phosphorylated at Tyrosine 96.
靶标信息
B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker protein; Cytoplasmic adapter protein; Lymphocyte antigen 57; MGC111051; SLP-65; Src homology 2 domain-containing leukocyte protein of 65 kDa
基因别名: BASH; Bca; BLNK; Ly-57; Ly57; Lyw-57; SLP-65; SLP65
UniProt ID: (Mouse) Q9QUN3
Entrez Gene ID: (Mouse) 17060
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