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Invitrogen
Phospho-CD32 (Tyr288) Polyclonal Antibody
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FIGURE: 1 / 2
Phospho-CD32 (Tyr288) Antibody (PA5-105099) in IHC (P)
Immunohistochemistry analysis of Phospho-CD32 (Tyr288) in rat heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-CD32 (Tyr288) polyclonal antibody (Product # PA5-105099) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-105099
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FCGR2A(Accession P12318), corresponding to amino acid residues around phosphorylated Tyr288.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of CD32 only when phosphorylated at Tyr288.
Target Information
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD16; CD32; CD32 receptor 2; CD32 receptor 2a; CDw32; Fc fragment of IgG low affinity IIa receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc receptor, IgG, low affinity IIb; Fc receptor, IgG, low affinity III; FC-gamma RII; Fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma RII-c; Fc-gamma RIII; Fc-gamma-RIIa; Fc-gamma-RIIb; Fc-gamma-RIIc; FcRII; FcRIII; FGFR2B; IgG Fc receptor II beta; IgG Fc receptor II-a; IgG Fc receptor II-b; IgG Fc receptor II-c; IgG Fc receptor III; Low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-a; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; Low affinity immunoglobulin gamma Fc region receptor III; MGC23887; MGC30032; RP11-5K23.6
Gene Aliases: CD32; FCG2; FcgammaRIIB2; Fcgr2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; Fcgr3; Fcgr3a; FCRII; IGFR2
UniProt ID: (Rat) P27645, (Rat) Q63203
Entrez Gene ID: (Rat) 116591, (Rat) 289211
nerve development
Fc-gamma receptor signaling pathway
negative regulation of type I hypersensitivity
immune complex clearance
negative regulation of immunoglobulin production
negative regulation of inflammatory response to antigenic stimulus
negative regulation of acute inflammatory response to antigenic stimulus
negative regulation of humoral immune response mediated by circulating immunoglobulin
receptor-mediated endocytosis
phagocytosis, engulfment
defense response
immune response
cell surface receptor signaling pathway
response to bacterium
immunoglobulin mediated immune response
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of B cell proliferation
response to estradiol
endocytic recycling
negative regulation of interleukin-10 production
negative regulation of neutrophil apoptotic process
mast cell activation
negative regulation of phagocytosis
positive regulation of phagocytosis
negative regulation of immune response
cellular response to molecule of bacterial origin
cellular response to lipopolysaccharide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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