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Invitrogen
Phospho-FBP1 (Tyr265) Polyclonal Antibody
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FIGURE: 1 / 2
Phospho-FBP1 (Tyr265) Antibody (PA5-105335) in WB
Western blot analysis of Phospho-FBP1 (Tyr265) in mouse kidney tissue (Lane 1: treated with phospho-blocking peptide; Lane 2: treated with non-phospho-blocking peptide). Samples were incubated with Phospho-FBP1 (Tyr265) polyclonal antibody (Product # PA5-105335).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-105335
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FBP1(Accession P09467), corresponding to amino acid residues around phosphorylated Tyr265.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of FBP1 only when phosphorylated at Tyr265.
Target Information
Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 3; EC 3.1.3.11; FBP 1; FBPase 1; FBPase liver; fructose 1,6-bisphosphatase (EC 3.1.3.11); fructose-1; fructose-1,6- biphosphatase 1; fructose-1,6-bisphosphatase isozyme 3; Fructose-16- biphosphatase; GIG17; growth-inhibiting protein 17; liver FBPase; unnamed protein product
Gene Aliases: FBP; Fbp-2; Fbp2; Fbp3; Fdp
UniProt ID: (Human) P09467, (Mouse) Q9QXD6, (Rat) P19112
Entrez Gene ID: (Human) 2203, (Mouse) 14121, (Rat) 24362
negative regulation of transcription from RNA polymerase II promoter
carbohydrate metabolic process
fructose metabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
regulation of gluconeogenesis
negative regulation of cell growth
response to nutrient levels
cellular response to insulin stimulus
negative regulation of glycolytic process
negative regulation of Ras protein signal transduction
cellular response to magnesium ion
cellular response to cAMP
cellular response to xenobiotic stimulus
cellular hyperosmotic salinity response
cellular hypotonic salinity response
cellular response to raffinose
cellular response to phorbol 13-acetate 12-myristate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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