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Invitrogen
Phospho-PAX7 (Ser203) Polyclonal Antibody
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FIGURE: 1 / 4
Phospho-PAX7 (Ser203) Antibody (PA5-105359) in ICC/IF
Immunofluorescent analysis of Phospho-PAX7 (Ser203) in HeLa cells(4h of LPS treatment). Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Phospho-PAX7 (Ser203) polyclonal antibody (Product # PA5-105359) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 ... View More
Product Details
PA5-105359
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PAX7(Accession P23759), corresponding to amino acid residues around phosphorylated Ser203.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of PAX7 only when phosphorylated at Ser203.
Target Information
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ37460; HuP1; paired box gene 7; paired box homeotic gene 7; Paired box protein Pax-7; paired box transcription factor PAX7; paired domain gene 7; PAX7 transcriptional factor; PAX7A; PAX7B
Gene Aliases: CMYO19; CMYP19; HUP1; MYOSCO; Pax-7; PAX7; PAX7B; RMS2
UniProt ID: (Human) P23759, (Mouse) P47239
Entrez Gene ID: (Human) 5081, (Mouse) 18509
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
chromatin remodeling
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
muscle organ development
skeletal muscle tissue development
organ morphogenesis
regulation of cell fate commitment
regulation of gene expression
skeletal muscle satellite cell commitment
spinal cord association neuron differentiation
dorsal/ventral neural tube patterning
positive regulation of histone methylation
regulation of protein binding
skeletal muscle tissue regeneration
positive regulation of transcription from RNA polymerase II promoter
neuron fate commitment
embryonic skeletal system development
cartilage development
muscle tissue morphogenesis
positive regulation of myoblast proliferation
nervous system development
anatomical structure morphogenesis
skeletal muscle satellite cell differentiation
negative regulation of apoptotic process
regulation of chromatin organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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