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Invitrogen
Phospho-delta Catenin (Tyr280) Polyclonal Antibody
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图: 1 / 4
Phospho-delta Catenin (Tyr280) Antibody (PA5-105410) in ICC/IF
Immunocytochemistry analysis of Phospho-delta Catenin (Tyr280) in H2O2 treated HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-delta Catenin (Tyr280) polyclonal antibody (Product # PA5-105410) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-105410
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CTNND1(Accession O60716), corresponding to amino acid residues around phosphorylated Tyr280.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of CTNND1 only when phosphorylated at Tyr280.
靶标信息
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; Catenin delta-1; catenin src; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(cas); p120(ctn); p120-catenin
基因别名: AA409437; AU019353; Catns; Ctnnd; CTNND1; KIAA0384; mKIAA0384; P120
UniProt ID: (Mouse) P30999
Entrez Gene ID: (Mouse) 12388, (Rat) 311163
morphogenesis of a polarized epithelium
transcription, DNA-templated
regulation of transcription, DNA-templated
cell adhesion
salivary gland morphogenesis
Wnt signaling pathway
single organismal cell-cell adhesion
keratinocyte differentiation
epithelial cell differentiation involved in salivary gland development
negative regulation of canonical Wnt signaling pathway
brain development
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