Invitrogen

Phospho-MPZL1 (Tyr260) Polyclonal Antibody

Name: Phospho-MPZL1 (Tyr260) Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-105440
Availability: InStock

查看其他12个MPZL1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (3)

Phospho-MPZL1 (Tyr260) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Phospho-MPZL1 (Tyr260) Antibody (PA5-105440) in IHC (P)

Immunohistochemistry analysis of paraffin-embedded Phospho-MPZL1 (Tyr260) in human kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-MPZL1 (Tyr260) polyclonal antibody (Product # PA5-105440) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.

Phospho-MPZL1 (Tyr260) Antibody in Western Blot (WB)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image Phospho-MPZL1 (Tyr260) Polyclonal Antibody

产品信息

PA5-105440

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human MPZL1(Accession O95297), corresponding to amino acid residues around phosphorylated Ser260.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

sequential chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2816868

产品详细信息

Antibody detects endogenous levels of PZR only when phosphorylated at Ser260.

靶标信息

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

仅用于科研。不用于诊断过程。未经明确授权不得转售。