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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of FGFR1/2/3/4 only when phosphorylated at Tyr653+Tyr654.
This gene encodes a protein that is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Basic fibroblast growth factor receptor 1; bFGF-R; bFGF-R-1; BFGFR; c-fgr; CD331; CD332; CD333; CD334; CTLA-2-beta protein; FGF receptor-1; fgfr 1; FGFR-1; FGFR-2; FGFR-3; FGFR-4; Fibroblast growth factor receptor 1; Fibroblast growth factor receptor 2; Fibroblast growth factor receptor 3; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; FLT-2; Fms-like tyrosine kinase 2; heparin-binding growth factor receptor; K-sam; Keratinocyte growth factor receptor; KGFR; MFR; N-sam; Protein-tyrosine kinase receptor MPK-11; Proto-oncogene c-Fgr
基因别名: AU043015; AW208770; AW556123; BEK; bFGF-R-1; BFGFR; c-fgr; CD333; CEK; Eask; Ect1; FGFBR; Fgfr-1; Fgfr-2; Fgfr-3; Fgfr-4; Fgfr-7; FGFR1; FGFR2; FGFR3; FGFR4; Fgfr7; FLG; Flg-2; Flt-2; FLT2; FR3; HBGFR; Hspy; JTK2; JTK4; KGFR; KGFRTr; KSAM; MFR; Mfr3; Mpk-11; sam3; svs; TKF
UniProt ID: (Rat) Q04589, (Mouse) P16092, (Mouse) P21803, (Rat) Q498D6, (Mouse) Q03142
Entrez Gene ID: (Rat) 79114, (Mouse) 14182, (Mouse) 14183, (Rat) 25022, (Rat) 84489, (Mouse) 14184, (Rat) 25114, (Mouse) 14186