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Invitrogen
Phospho-DUSP16 (Ser446) Polyclonal Antibody
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Phospho-DUSP16 (Ser446) Antibody (PA5-106012) in IHC (P)
Immunohistochemistry analysis of Phospho-DUSP16 (Ser446) in rat stomach tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-DUSP16 (Ser446) polyclonal antibody (Product # PA5-106012) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106012
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DUSP16(Accession Q9BY84), corresponding to amino acid residues around phosphorylated Ser446.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
sequential chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of DUSP16 only when phosphorylated at Ser446.
靶标信息
Dual-specificity phosphatases constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP16 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK proteins ERK, JNK, and p38 with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dual specificity protein phosphatase 16; MAP kinase phosphatase 7; MAP kinase phosphatase-7; map kinase phosphatase-M; MGC129701; MGC129702; Mitogen-activated protein kinase phosphatase 7
基因别名: 3830417M17Rik; AW558566; D6Ertd213e; DUSP16; KIAA1700; MKP-7; MKP7; Mkpm
Entrez Gene ID: (Mouse) 70686, (Rat) 297682
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