Invitrogen

Phospho-PAK6 (Ser165) Polyclonal Antibody

Name: Phospho-PAK6 (Ser165) Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-106021
Availability: InStock

查看其他12个PAK6抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

Phospho-PAK6 (Ser165) Antibody in Western Blot (WB)

图: 1 / 1

Phospho-PAK6 (Ser165) Antibody (PA5-106021) in WB

Western blot analysis of Phospho-PAK6 (Ser165) in mouse lung. Samples were incubated with Phospho-PAK6 (Ser165) polyclonal antibody (Product # PA5-106021).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

Immunogen image

Immunogen Image Phospho-PAK6 (Ser165) Polyclonal Antibody

产品信息

PA5-106021

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human PAK6(Accession Q9NQU5), corresponding to amino acid residues around phosphorylated Ser165.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

sequential chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2817420

产品详细信息

Antibody detects endogenous levels of PAK6 only when phosphorylated at Ser165.

靶标信息

PAK6 is a serine/threonine kinase expressed in the testis and prostate. It associates with both the estrogen and androgen receptors. The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.

仅用于科研。不用于诊断过程。未经明确授权不得转售。