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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of PRC1 only when phosphorylated at Thr470.
This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC1671; MGC3669; prc1; Protein regulator of cytokinesis 1
基因别名: D7Ertd348e; PRC1
UniProt ID: (Mouse) Q99K43
Entrez Gene ID: (Mouse) 233406