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Invitrogen
CPT1A Polyclonal Antibody
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CPT1A Antibody (PA5-106270) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded CPT1A in human kidney tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with CPT1A polyclonal antibody (Product # PA5-106270) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106270
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CPT1A(Accession P50416), corresponding to amino acid residues R601-S651.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CPT1A.
靶标信息
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Carnitine O-palmitoyltransferase 1, liver isoform; Carnitine O-palmitoyltransferase I, liver isoform; Carnitine palmitoyltransferase 1 alpha, liver isoform; carnitine palmitoyltransferase 1, liver; Carnitine palmitoyltransferase 1A; CPT 1; CPT I; CPT1 L; CPT1-L; CPTI-L; L-CPT I; Succinyltransferase CPT1A
基因别名: C730027G07; Cpt-1; CPT-Ia; CPT1; CPT1A; CPTI
UniProt ID: (Mouse) P97742, (Rat) P32198
Entrez Gene ID: (Mouse) 12894, (Rat) 25757
long-chain fatty acid metabolic process
glucose metabolic process
lipid metabolic process
fatty acid metabolic process
triglyceride metabolic process
transport
carnitine metabolic process
positive regulation of fatty acid beta-oxidation
eating behavior
regulation of fatty acid oxidation
regulation of insulin secretion
protein homooligomerization
fatty acid beta-oxidation
response to organic cyclic compound
epithelial cell differentiation
regulation of fatty acid beta-oxidation
response to drug
cellular response to fatty acid
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