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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total REEP5.
REEP5 (receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2 or D5S346, is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the parm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: deleted in polyposis 1; GP106; Polyposis locus protein 1; Polyposis locus protein 1 homolog; Protein TB2; protein TB2 homolog; receptor expression enhancing protein 5; Receptor expression-enhancing protein 5
基因别名: AI324241; AU022809; AW495741; C5orf18; DP1; DP1/TB2; R74856; REEP5; TB2; TB2/DP1
UniProt ID: (Rat) B2RZ37
Entrez Gene ID: (Rat) 364838, (Mouse) 13476