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Invitrogen
SH2D1B Polyclonal Antibody
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SH2D1B Antibody (PA5-106376) in IHC (P)
Immunohistochemistry analysis of SH2D1B in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SH2D1B polyclonal antibody (Product # PA5-106376) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106376
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human SH2D1B(Accession O14796), corresponding to amino acid residues K85-P132.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total SH2D1B.
靶标信息
SH2D1B plays a role in controlling signal transduction through at least four receptors, CD84, CD150, CD229 and CD244, expressed on the surface of professional antigen-presenting cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EWS/FLI1 activated transcript 2; EWS/FLI1-activated transcript 2; SH2 domain containing 1B; SH2 domain protein 1B1; SH2 domain-containing protein 1B
基因别名: EAT-2; EAT-2A; Eat2; Eat2a; RGD1563935; Sh2d1b; Sh2d1b1
Entrez Gene ID: (Rat) 501869, (Mouse) 26904
leukocyte activation involved in immune response
positive regulation of natural killer cell mediated immunity
natural killer cell inhibitory signaling pathway
positive regulation of signal transduction
peptidyl-tyrosine phosphorylation
negative regulation of interferon-gamma production
positive regulation of innate immune response
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of peptidyl-tyrosine phosphorylation
biological_process
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