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Invitrogen
FOXN4 Polyclonal Antibody
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FIGURE: 1 / 3
FOXN4 Antibody (PA5-106666) in WB
Western blot analysis of FOXN4 in extracts from various samples. Samples were incubated with FOXN4 polyclonal antibody (Product # PA5-106666). Lane 1: 3t3-l1 cells, blocked with antigen-specific peptides; Lane 2: 3t3-l1 cells; Lane 3: Pc12 cells (h2o2 treatment).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106666
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FOXN4(Accession Q96NZ1), corresponding to amino acid residues D413-S463.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total FOXN4.
Target Information
Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM, Mar 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: forkhead/winged helix transcription factor FOXN4; sli; slipjig; transcription factor; unnamed protein product
UniProt ID: (Human) Q96NZ1, (Mouse) Q8K3Q3
Entrez Gene ID: (Human) 121643, (Rat) 288736, (Mouse) 116810
heart looping
regulation of transcription, DNA-templated
regulation of heart contraction
retina layer formation
ventral spinal cord interneuron differentiation
amacrine cell differentiation
atrioventricular canal development
positive regulation of transcription from RNA polymerase II promoter
ventral spinal cord interneuron fate commitment
cell differentiation
neuron fate commitment
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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