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Invitrogen
ALG2 Polyclonal Antibody
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ALG2 Antibody (PA5-109379) in WB
Western blot analysis of ALG2 in extracts of various cell lines. Samples were incubated with ALG2 Polyclonal antibody (Product # PA5-109379) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-109379
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.78 mg/mL
规格
78 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DVLYPSLNVT SFDSVVPEKL DDLVPKGKKF LLLSINRYER KKNLTLALEA LVQLRGRLTS QDWERVHLIV AGGYDERVLE NVEHYQELKK MVQQSDLGQY VTFLRSFSDK QKISLLHSCT CVLYTPSNEH FGIVPLEAMY MQCPVIAVNS GGPLESIDHS VTGFLCEPDP VHFSEAIEKF IREPSLKATM GLAGRARVKE KFSPEAFTEQ LYRYVTKLLV
靶标信息
ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1, 3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1, 3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha-1,3-mannosyltransferase ALG2; Alpha-1,3/1,6-mannosyltransferase ALG2; asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase); Asparagine-linked glycosylation protein 2 homolog; FLJ14511; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase
基因别名: 1110018A23Rik; 1300013N08Rik; ALG2; ALPG2; CDGIi; MNCb-5081; UNQ666/PRO1298
UniProt ID: (Mouse) Q9DBE8
Entrez Gene ID: (Mouse) 56737
alpha-1,3-mannosyltransferase activity
GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
glycolipid 6-alpha-mannosyltransferase activity
protein heterodimerization activity
protein N-terminus binding
calcium-dependent protein binding
transferase
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