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Invitrogen
CPB2 Polyclonal Antibody
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CPB2 Antibody (PA5-109580) in WB
Western blot analysis of CPB2 in extracts of various cell lines. Samples were incubated with CPB2 Polyclonal antibody (Product # PA5-109580) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-109580
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 115-365 of human CPB2 (NP_001863.2).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.15 mg/mL
规格
15 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ASASYYEQYH SLNEIYSWIE FITERHPDML TKIHIGSSFE KYPLYVLKVS GKEQAAKNAI WIDCGIHARE WISPAFCLWF IGHITQFYGI IGQYTNLLRL VDFYVMPVVN VDGYDYSWKK NRMWRKNRSF YANNHCIGTD LNRNFASKHW CEEGASSSSC SETYCGLYPE SEPEVKAVAS FLRRNINQIK AYISMHSYSQ HIVFPYSYTR SKSKDHEELS LVASEAVRAI EKTSKNTRYT HGHGSETLYL A
靶标信息
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Carboxypeptidase B2; Carboxypeptidase U; CPU; pCPB; Plasma carboxypeptidase B; TAFI; Thrombin-activable fibrinolysis inhibitor
基因别名: CPB2
Entrez Gene ID: (Human) 1361
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