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Invitrogen
GUCY2D Polyclonal Antibody
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GUCY2D Antibody (PA5-109800) in WB
Western blot analysis of GUCY2D in extracts of various cell lines. Samples were incubated with GUCY2D Polyclonal antibody (Product # PA5-109800) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-109800
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 52-350 of human GUCY2D (NP_000171.1).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.58 mg/mL
规格
58 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AVFTVGVLGP WACDPIFSRA RPDLAARLAA ARLNRDPGLA GGPRFEVALL PEPCRTPGSL GAVSSALARV SGLVGPVNPA ACRPAELLAE EAGIALVPWG CPWTQAEGTT APAVTPAADA LYALLRAFGW ARVALVTAPQ DLWVEAGRSL STALRARGLP VASVTSMEPL DLSGAREALR KVRDGPRVTA VIMVMHSVLL GGEEQRYLLE AAEELGLTDG SLVFLPFDTI HYALSPGPEA LAALANSSQL RRAHDAVLTL TRHCPSEGSV LDSLRRAQER RELPSDLNLQ QVSPLFGTI
靶标信息
Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: central areolar choroidal dystrophy; cone rod dystrophy 6; guanylate cyclase 2D, membrane (retina-specific); guanylate cyclase 2E, pseudogene; guanylate cyclase, olfactory; guanylyl cyclase 2d; guanylyl cyclase D; olfactory guanylyl cyclase GC-D; retinal guanylate cyclase 1; rod outer segment membrane guanylate cyclase; ROS-GC; unnamed protein product
基因别名: CACD; CACD1; CG-E; CORD5; CORD6; CSNB1I; CYGD; GC-D; GUC1A4; GUC2D; Gucy2e; Gucy2ep; LCA; LCA1; ONE-GC; RCD2; retGC; RETGC-1; ROS-GC1; ROSGC
UniProt ID: (Human) Q02846, (Mouse) A0A0U1RPR8, (Rat) P51839
Entrez Gene ID: (Human) 3000, (Mouse) 14918, (Rat) 113911
peptide receptor activity
guanylate cyclase activity
protein kinase activity
protein binding
ATP binding
phosphorus-oxygen lyase activity
signaling receptor activity
identical protein binding
protein homodimerization activity
protein heterodimerization activity
olfactory receptor activity
odorant binding
natriuretic peptide receptor activity
detection of carbon dioxide
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway
sensory perception of smell
olfactory learning
cyclic nucleotide biosynthetic process
intracellular signal transduction
olfactory behavior
detection of stimulus involved in sensory perception
detection of chemical stimulus involved in sensory perception of smell
visual perception
regulation of rhodopsin mediated signaling pathway
cGMP metabolic process
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